Director: Darren Aronofsky

Plot: Drugs. They consume mind, body and soul. Once you're hooked, you're hooked. Four lives. Four addicts. Four failures. Despite their aspirations of greatness, they succumb to their addictions. Watching the addicts spiral out of control, we bear witness to the dirtiest, ugliest portions of the underworld addicts reside in.

Cast: Ellen Burstyn ,Jared Leto ,Jennifer Connelly ,Marlon Wayans ,Christopher McDonald